It is now time to begin the study of personal genome services based on the interdisciplinary theories and technologies of genomics and artificial intelligence (AI). Although recently much attention has been given to personal genome services for realizing personal medicine, little systematic research has been done on their communication and computational aspects for intelligent wellness service in AI communities. We believe that the intelligent personal genome services of the future need to include an understanding of how the knowledge of genetic risk influences people's behavior. This paper proposes the concept of MyFinder, a new framework for realizing an intimate personal genome service with AI technologies. This paper also describes the grand challenge problems of personal genome services that the AI and genomics communities should tackle jointly.